Pence is adding Guatemala to his third trip to Latin America in less than a year. The trip comes after the recent volcanic eruption that killed at least 110 people and left another 200 missing.
Pence says the U.S. is helping transport burn victims for treatment and sending emergency aid at the request of President Jimmy Morales' government.
The vice president has said he intends to bring attention during his trip to the deepening humanitarian crisis in Venezuela.
Pence made his remarks Thursday at the National Hispanic Prayer Breakfast.
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